The world's first agentic AI genomic discovery platform.
This isn't just a chatbot. Inference Agents don't summarize papers or rehash what's already known. They make novel discoveries from foundational data using first principles. With AI-powered tools, we're transforming how pharma R&D teams use human data to discover targets and make clinical programs successful, getting life-saving treatments to patients faster.
Approach
Measuring target levels in patient samples tells you what's different in disease—not what's driving it. That correlation-based approach has led drug discovery astray for decades. Human genetics is different: it reveals causal mechanisms, showing which genes actually influence disease risk and how to modulate them safely.
Drugs with genetic support are 2.6 times more likely to succeed in clinical trials than those without.
In 2021, two-thirds of drugs approved had human genetic evidence supporting their target.
Genetically validated targets have 50% lower odds of causing adverse effects in clinical development.
Interactive tools that query live data across hundreds of millions of associations in seconds. Run colocalization on demand. Combine studies in real time. See the data behind every result, then ask the next question immediately.
No pre-run reports or cached results mean you can bring your own data and start querying immediately. No waiting.
Discovery happens iteratively. Your platform should too.
Applications
Inference supports pharmaceutical research across the entire development lifecycle, from early target identification through clinical trial design and business development.
Identify novel therapeutic targets through hypotheses backed by strong human genetic evidence. Uncover the molecular mechanisms driving disease and prioritize genes with clear druggable potential.
Identify biomarkers for target engagement and patient stratification. Profile safety liabilities using comprehensive genetic association data across thousands of phenotypes.
Identify new indications for existing assets, particularly those that fail on efficacy but demonstrate good safety. Prioritize programs based on human genetic validation, the strongest predictor of clinical success.
Why Inference
Inference isn't just another analytics tool. It's a completely different approach to drug discovery. With Inference, we built the platform we wish existed when we started Variant Bio. Our team combines deep statistical genetics expertise with enterprise grade software engineering. We run our own drug discovery programs, and we needed these tools to do it.
Major public genetic and functional genomic datasets harmonized alongside proprietary datasets from studies with underrepresented populations. Billions of associations, instantly queryable.
Explorers enable dynamic queries across massive datasets with a comprehensive API powering every feature. Nothing is locked behind static reports.
Tools that can summarize vast datasets, see connections humans can't, and make predictions from complex multi-omic data, solving real problems and increasing productivity.
Inference powers collaborations with our pharma partners representing over $200 million in deal value. To explore how Inference can accelerate your research, get in touch.
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